The use of subject-specific head-casts allows for acquisition of high SNR MEG data. Using computer simulations I showed that with these head-casts it is, in principle, possible to localize data recorded with MEG sensors to deep or superficial cortical laminae; a possibility that I then realized, non-invasively in the human brain, demonstrating the laminar- and frequency-specific correlates of action selection for the first time.
Laminar MEG
Laminar MEG
Publications
Estimates of cortical column orientation improve MEG source inversion
BACKGROUND Determining the anatomical source of brain activity non-invasively measured from EEG or MEG sensors is challenging. In order …
Lamina-specific cortical dynamics in human visual and sensorimotor cortices
Distinct anatomical and spectral channels are thought to play specialized roles in the communication within cortical networks. While …
Non-invasive laminar inference with MEG: Comparison of methods and source inversion algorithms
Magnetoencephalography (MEG) is a direct measure of neuronal current flow; its anatomical resolution is therefore not constrained by …
Quantifying the performance of MEG source reconstruction using resting state data
In magnetoencephalography (MEG) research there are a variety of inversion methods to transform sensor data into estimates of brain …
Flexible head-casts for high spatial precision MEG
BACKGROUND In combination with magnetoencephalographic (MEG) data, accurate knowledge of the brain’s structure and location …