computational model

Computational Neurostim

Simulating the effects of noninvasive brain stimulation on behavior.

Sensorimotor beta bursts: lamina-specificity and function

Response repetition biases in human perceptual decisions are explained by activity decay in competitive attractor models

Animals and humans have a tendency to repeat recent choices, a phenomenon known as choice hysteresis. The mechanism for this choice bias remains unclear. Using an established, biophysically informed model of a competitive attractor network for …

Selective alteration of human value decisions with medial frontal tDCS is predicted by changes in attractor dynamics

During value-based decision making, ventromedial prefrontal cortex (vmPFC) is thought to support choices by tracking the expected gain from different outcomes via a competition-based process. Using a computational neurostimulation approach we asked …

Understanding the behavioural consequences of noninvasive brain stimulation

Transcranial electrical stimulation (tES) influences neural activity in a way that can elicit behavioural change but may also improve high-level cognition or ameliorate symptoms in neuropsychiatric disorders. However, the current fervour for tES …

A Biologically Plausible Computational Theory for Value Integration and Action Selection in Decisions with Competing Alternatives

Decision making is a vital component of human and animal behavior that involves selecting between alternative options and generating actions to implement the choices. Although decisions can be as simple as choosing a goal and then pursuing it, humans …

Learning to grasp and extract affordances: the Integrated Learning of Grasps and Affordances (ILGA) model

The activity of certain parietal neurons has been interpreted as encoding affordances (directly perceivable opportunities) for grasping. Separate computational models have been developed for infant grasp learning and affordance learning, but no …

Understanding the nonlinear physiological and behavioral effects of tDCS through computational neurostimulation

Despite the success of noninvasive brain stimulation (NIBS), the mechanism of action through which different stimulation techniques interact with information processing in targeted neural circuits largely remains unknown. Applying neurostimulation in …

A Neuroinformatics of Brain Modeling and its Implementation in the Brain Operation Database BODB

We present principles for an integrated neuroinformatics framework which makes explicit how models are grounded on empirical evidence, explain (or not) existing empirical results and make testable predictions. The new ontological framework makes …

Modeling the BOLD correlates of competitive neural dynamics

Winner-take-all models are commonly used to model decision-making tasks where one outcome must be selected from several competing options. Related random walk and diffusion models have been used to explain such processes and apply them to …